The 34-year-old finished 11th at the Boston Marathon in April.
For his second marathon, the former track star is taking a completely new approach to racing.
The track standout is committed to the marathon heading into the 2016 Olympic year.
Ethiopian Ejegayehu Dibaba has pulled out due to injury.
Track specialists Molly Huddle and Sally Kipyego will make their half-marathon debuts on the women's side.
The newly minted marathoner is ready to mix it up against a stacked men's field.
He says he's feeling healthy and ready following his marathon debut.
Matt Tegenkamp is currently the man to beat on November 17.
The 31-year-old defended his 20K title in New Haven last weekend.
A strong international field will line up in The Windy City on October 13.