The 10,000m silver medalist from Oregon hopes will square off against the 5,000m silver medalist from Ethiopia.
She says she's fit and confident.
Many world-leading performances posted Saturday night in Boston.
They are training partners and will be rivals next month.
Manzano, Reid, Chelanga will race in Boston on Saturday.
Two of the fastest non-African milers are squaring off in Boston.
Annual event will take place on February 5.