American -record holder in the mile, Alan Webb, is entered.
Injuries had sidelined her racing for 14 months.
Loaded fields on both the men's and women's sides.
The Ethiopian closed with a blistering final lap, winning by over 5 seconds to cap off the first day of competition.
The 26-year-old will run both the 10,000 and 5,000 meters.
Lopez Lomong won the 5000m in 13:11.63.
Over 13,000 runners finish 75th edition of the historic race.
Iconic 4.748-mile Thanksgiving Day race set for tomorrow morning.
Kenyan Sally Kipyego, who trains with the Oregon Track Club Elite, finished third in today's Dash To The Finish Line 5K, running 16:03.